Glucocorticoid receptor alpha translational isoforms as mediators of early adversities and negative emotional states

Childhood trauma (CT) increases the risk for psychopathology through disturbed acquisition and extinction of fear. The effects of CT are mediated by abnormalities of the hypothalamic-pituitary-adrenal axis and glucocorticoid receptor (GR). Since, the alterations in GRα translational isoforms have be...

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Veröffentlicht in:Prog Neuropsychopharmacol Biol Psychiatry
Hauptverfasser: Adzic, Miroslav, Glavonic, Emilija, Nesic, Milica J., Milosavljevic, Minja, Mihaljevic, Marina, Petrovic, Zorica, Pavlovic, Zorana, Brkic, Zeljka, Francija, Ester, Soldatovic, Ivan, Mitic, Milos, Radulovic, Jelena, Maric, Nadja P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6383671/
https://ncbi.nlm.nih.gov/pubmed/30580022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pnpbp.2018.12.011
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