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Modulation of c-Jun N-Terminal Kinase Signaling and Specific Glucocorticoid Receptor Phosphorylation in the Treatment of Major Depression
Glucocorticoid resistance is a common finding in major depressive disorder. Increased glucocorticoid receptor (GR) phosphorylation at serine 226 is associated with increased glucocorticoid resistance. Previously we have demonstrated that depressed patients exhibit higher levels of GR phosphorylated...
Shranjeno v:
| izdano v: | Med Hypotheses |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2015
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4549182/ https://ncbi.nlm.nih.gov/pubmed/26052031 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mehy.2015.05.015 |
| Oznake: |
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