Modulation of c-Jun N-Terminal Kinase Signaling and Specific Glucocorticoid Receptor Phosphorylation in the Treatment of Major Depression

Glucocorticoid resistance is a common finding in major depressive disorder. Increased glucocorticoid receptor (GR) phosphorylation at serine 226 is associated with increased glucocorticoid resistance. Previously we have demonstrated that depressed patients exhibit higher levels of GR phosphorylated...

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Enregistré dans:
Détails bibliographiques
Publié dans:Med Hypotheses
Auteurs principaux: Jovicic, Milica J., Lukic, Iva, Radojcic, Marija, Adzic, Miroslav, Maric, Nadja P.
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4549182/
https://ncbi.nlm.nih.gov/pubmed/26052031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mehy.2015.05.015
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