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Modulation of c-Jun N-Terminal Kinase Signaling and Specific Glucocorticoid Receptor Phosphorylation in the Treatment of Major Depression

Glucocorticoid resistance is a common finding in major depressive disorder. Increased glucocorticoid receptor (GR) phosphorylation at serine 226 is associated with increased glucocorticoid resistance. Previously we have demonstrated that depressed patients exhibit higher levels of GR phosphorylated...

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Vydáno v:Med Hypotheses
Hlavní autoři: Jovicic, Milica J., Lukic, Iva, Radojcic, Marija, Adzic, Miroslav, Maric, Nadja P.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4549182/
https://ncbi.nlm.nih.gov/pubmed/26052031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mehy.2015.05.015
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