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Modulation of c-Jun N-Terminal Kinase Signaling and Specific Glucocorticoid Receptor Phosphorylation in the Treatment of Major Depression

Glucocorticoid resistance is a common finding in major depressive disorder. Increased glucocorticoid receptor (GR) phosphorylation at serine 226 is associated with increased glucocorticoid resistance. Previously we have demonstrated that depressed patients exhibit higher levels of GR phosphorylated...

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發表在:Med Hypotheses
Main Authors: Jovicic, Milica J., Lukic, Iva, Radojcic, Marija, Adzic, Miroslav, Maric, Nadja P.
格式: Artigo
語言:Inglês
出版: 2015
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4549182/
https://ncbi.nlm.nih.gov/pubmed/26052031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mehy.2015.05.015
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