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Simvastatin Improves Cardiac Hypertrophy in Diabetic Rats by Attenuation of Oxidative Stress and Inflammation Induced by Calpain-1-Mediated Activation of Nuclear Factor-κB (NF-κB)

BACKGROUND: Simvastatin, an HMG-CoA reductase inhibitor, has been reported to exert multiple protective effects on the cardiovascular system. However, the molecular mechanism remains to be examined. The present study was designed to study the effects of simvastatin on cardiac hypertrophy in diabetic...

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שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Med Sci Monit
Main Authors: Han, Qianqian, Liu, Qianqian, Zhang, Hui, Lu, Meili, Wang, Hongxin, Tang, Futian, Zhang, Yingjie
פורמט: Artigo
שפה:Inglês
יצא לאור: International Scientific Literature, Inc. 2019
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC6383435/
https://ncbi.nlm.nih.gov/pubmed/30767945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.913244
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