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Simvastatin Improves Cardiac Hypertrophy in Diabetic Rats by Attenuation of Oxidative Stress and Inflammation Induced by Calpain-1-Mediated Activation of Nuclear Factor-κB (NF-κB)

BACKGROUND: Simvastatin, an HMG-CoA reductase inhibitor, has been reported to exert multiple protective effects on the cardiovascular system. However, the molecular mechanism remains to be examined. The present study was designed to study the effects of simvastatin on cardiac hypertrophy in diabetic...

詳細記述

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書誌詳細
出版年:Med Sci Monit
主要な著者: Han, Qianqian, Liu, Qianqian, Zhang, Hui, Lu, Meili, Wang, Hongxin, Tang, Futian, Zhang, Yingjie
フォーマット: Artigo
言語:Inglês
出版事項: International Scientific Literature, Inc. 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6383435/
https://ncbi.nlm.nih.gov/pubmed/30767945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.913244
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