Tyrosine Kinase Inhibitor Imatinib Mesylate Alters DMBA-Induced Early Onco/Suppressor Gene Expression with Tissue-Specificity in Mice

Tyrosine kinases play crucial roles in cellular development and tumorigenesis. Tyrosine kinase inhibitors (TKIs) are effective and widely used drug molecules in targeted cancer therapies. Altered expressions of protooncogenes and tumor suppressor genes after DMBA (7,12-dimethylbenz[a]anthracene) tre...

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Detalhes bibliográficos
Publicado no:Biomed Res Int
Main Authors: Gergely, Péter Attila, Murnyák, Balázs, Bencze, János, Kurucz, Andrea, Varjas, Timea, Gombos, Katalin, Hortobágyi, Tibor
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6383434/
https://ncbi.nlm.nih.gov/pubmed/30882001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/8670398
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