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Fold-Change Detection of NF-κB at Target Genes with Different Transcript Outputs

The transcription factor nuclear factor (NF)-κB promotes inflammatory and stress-responsive gene transcription across a range of cell types in response to the cytokine tumor necrosis factor (TNF). Although NF-κB signaling exhibits significant variability across single cells, some target genes suppor...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Biophys J
Hauptverfasser: Wong, Victor C., Mathew, Shibin, Ramji, Ramesh, Gaudet, Suzanne, Miller-Jensen, Kathryn
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Biophysical Society 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6382958/
https://ncbi.nlm.nih.gov/pubmed/30704857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2019.01.011
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