Association study in African-admixed populations across the Americas recapitulates asthma risk loci in non-African populations

Asthma is a complex disease with striking disparities across racial and ethnic groups. Despite its relatively high burden, representation of individuals of African ancestry in asthma genome-wide association studies (GWAS) has been inadequate, and true associations in these underrepresented minority...

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Publicado en:Nat Commun
Main Authors: Daya, Michelle, Rafaels, Nicholas, Brunetti, Tonya M., Chavan, Sameer, Levin, Albert M., Shetty, Aniket, Gignoux, Christopher R., Boorgula, Meher Preethi, Wojcik, Genevieve, Campbell, Monica, Vergara, Candelaria, Torgerson, Dara G., Ortega, Victor E., Doumatey, Ayo, Johnston, Henry Richard, Acevedo, Nathalie, Araujo, Maria Ilma, Avila, Pedro C., Belbin, Gillian, Bleecker, Eugene, Bustamante, Carlos, Caraballo, Luis, Cruz, Alvaro, Dunston, Georgia M., Eng, Celeste, Faruque, Mezbah U., Ferguson, Trevor S., Figueiredo, Camila, Ford, Jean G., Gan, Weiniu, Gourraud, Pierre-Antoine, Hansel, Nadia N., Hernandez, Ryan D., Herrera-Paz, Edwin Francisco, Jiménez, Silvia, Kenny, Eimear E., Knight-Madden, Jennifer, Kumar, Rajesh, Lange, Leslie A., Lange, Ethan M., Lizee, Antoine, Maul, Pissamai, Maul, Trevor, Mayorga, Alvaro, Meyers, Deborah, Nicolae, Dan L., O’Connor, Timothy D., Oliveira, Ricardo Riccio, Olopade, Christopher O., Olopade, Olufunmilayo, Qin, Zhaohui S., Rotimi, Charles, Vince, Nicolas, Watson, Harold, Wilks, Rainford J., Wilson, James G., Salzberg, Steven, Ober, Carole, Burchard, Esteban G., Williams, L. Keoki, Beaty, Terri H., Taub, Margaret A., Ruczinski, Ingo, Mathias, Rasika A., Barnes, Kathleen C.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2019
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6382865/
https://ncbi.nlm.nih.gov/pubmed/30787307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-08469-7
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