Inotilone from Inonotus linteus suppresses lung cancer metastasis in vitro and in vivo through ROS-mediated PI3K/AKT/MAPK signaling pathways

Metastasis is one of the main causes of mortality in cancer patients. Inotilone, a major component of Inonotus linteus, is a traditional Chinese medical herb. In this study, MTT results showed that inotilone had no obvious cytotoxicity. Animal model results revealed that inotilone suppressed cancer...

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Vydáno v:Sci Rep
Hlavní autoři: Chao, Wei, Deng, Jeng-Shyan, Li, Pei-Ying, Kuo, Yueh-Hsiung, Huang, Guan-Jhong
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6382761/
https://ncbi.nlm.nih.gov/pubmed/30787353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-38959-z
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