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Anti-Inflammatory Activities of Inotilone from Phellinus linteus through the Inhibition of MMP-9, NF-κB, and MAPK Activation In Vitro and In Vivo

Inotilone was isolated from Phellinus linteus. The anti-inflammatory effects of inotilone were studied by using lipopolysaccharide (LPS)-stimulated mouse macrophage RAW264.7 cells and λ-carrageenan (Carr)-induced hind mouse paw edema model. Inotilone was tested for its ability to reduce nitric oxide...

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Detalhes bibliográficos
Main Authors: Huang, Guan-Jhong, Huang, Shyh-Shyun, Deng, Jeng-Shyan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3348146/
https://ncbi.nlm.nih.gov/pubmed/22590514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0035922
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