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Shaoyao Gancao Tang (SG-Tang), a formulated Chinese medicine, reduces aggregation and exerts neuroprotection in spinocerebellar ataxia type 17 (SCA17) cell and mouse models

Spinocerebellar ataxia (SCA) type 17 is an autosomal dominant ataxia caused by expanded polyglutamine (polyQ) tract in the TATA-box binding protein (TBP). Substantial studies have shown involvement of compromised mitochondria biogenesis regulator peroxisome proliferator-activated receptor gamma-coac...

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Detalhes bibliográficos
Publicado no:Aging (Albany NY)
Main Authors: Chen, Chiung-Mei, Chen, Wan-Ling, Hung, Chen-Ting, Lin, Te-Hsien, Lee, Ming-Chung, Chen, I-Cheng, Lin, Chih-Hsin, Chao, Chih-Ying, Wu, Yih-Ru, Chang, Kuo-Hsuan, Hsieh-Li, Hsiu Mei, Lee-Chen, Guey-Jen
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6382417/
https://ncbi.nlm.nih.gov/pubmed/30760647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.101804
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