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Constitutive IP(3)R1-mediated Ca(2+) release reduces Ca(2+) store content and stimulates mitochondrial metabolism in mouse GV oocytes
In mammals, fertilization initiates Ca(2+) oscillations in metaphase II oocytes, which are required for the activation of embryo development. Germinal vesicle (GV) oocytes also display Ca(2+) oscillations, although these unfold spontaneously in the absence of any known agonist(s) and their function...
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| Udgivet i: | J Cell Sci |
|---|---|
| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Company of Biologists Ltd
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6382016/ https://ncbi.nlm.nih.gov/pubmed/30659110 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.225441 |
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