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Caffeine alleviates the deterioration of Ca(2+) release mechanisms and fragmentation of in vitro aged mouse eggs

The developmental competence of mammalian eggs is compromised by postovulatory aging. We and others found that in these eggs the intracellular calcium ([Ca(2+)](i)) responses required for egg activation and initiation of development are altered. Nevertheless, the mechanism(s) underlying this defecti...

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Detalhes bibliográficos
Main Authors: Zhang, Nan, Wakai, Takuya, Fissore, Rafael. A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3227013/
https://ncbi.nlm.nih.gov/pubmed/22095868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mrd.21366
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