A crucial role for Arf6 in the response of commissural axons to Slit

A switch in the response of commissural axons to the repellent Slit is crucial for ensuring that they cross the ventral midline only once. However, the underlying mechanisms remain to be elucidated. We have found that both endocytosis and recycling of Robo1 receptor are crucial for modulating Slit s...

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Detalhes bibliográficos
Publicado no:Development
Main Authors: Kinoshita-Kawada, Mariko, Hasegawa, Hiroshi, Hongu, Tsunaki, Yanagi, Shigeru, Kanaho, Yasunori, Masai, Ichiro, Mishima, Takayasu, Chen, Xiaoping, Tsuboi, Yoshio, Rao, Yi, Yuasa-Kawada, Junichi, Wu, Jane Y.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6382006/
https://ncbi.nlm.nih.gov/pubmed/30674481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.172106
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