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Lineage-specific reorganization of nuclear peripheral heterochromatin and H3K9me2 domains

Dynamic organization of chromatin within the three-dimensional nuclear space has been postulated to regulate gene expression and cell fate. Here, we define the genome-wide distribution of nuclear peripheral heterochromatin as a multipotent P19 cell adopts either a neural or a cardiac fate. We demons...

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Vydáno v:Development
Hlavní autoři: See, Kelvin, Lan, Yemin, Rhoades, Joshua, Jain, Rajan, Smith, Cheryl L., Epstein, Jonathan A.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Company of Biologists Ltd 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6382005/
https://ncbi.nlm.nih.gov/pubmed/30723106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.174078
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