Glycine Protects against Hypoxic-Ischemic Brain Injury by Regulating Mitochondria-Mediated Autophagy via the AMPK Pathway

Hypoxic-ischemic encephalopathy (HIE) is detrimental to newborns and is associated with high mortality and poor prognosis. Thus, the primary aim of the present study was to determine whether glycine could (1) attenuate HIE injury in rats and hypoxic stress in PC12 cells and (2) downregulate mitochon...

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Publicado en:Oxid Med Cell Longev
Autores principales: Cai, Chen-chen, Zhu, Jiang-hu, Ye, Li-xia, Dai, Yuan-yuan, Fang, Ming-chu, Hu, Ying-ying, Pan, Shu-lin, Chen, Si, Li, Pei-jun, Fu, Xiao-qin, Lin, Zhen-lang
Formato: Artigo
Lenguaje:Inglês
Publicado: Hindawi 2019
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6381570/
https://ncbi.nlm.nih.gov/pubmed/30881590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/4248529
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