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Glycine Protects against Hypoxic-Ischemic Brain Injury by Regulating Mitochondria-Mediated Autophagy via the AMPK Pathway

Hypoxic-ischemic encephalopathy (HIE) is detrimental to newborns and is associated with high mortality and poor prognosis. Thus, the primary aim of the present study was to determine whether glycine could (1) attenuate HIE injury in rats and hypoxic stress in PC12 cells and (2) downregulate mitochon...

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Detalhes bibliográficos
Publicado no:Oxid Med Cell Longev
Main Authors: Cai, Chen-chen, Zhu, Jiang-hu, Ye, Li-xia, Dai, Yuan-yuan, Fang, Ming-chu, Hu, Ying-ying, Pan, Shu-lin, Chen, Si, Li, Pei-jun, Fu, Xiao-qin, Lin, Zhen-lang
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6381570/
https://ncbi.nlm.nih.gov/pubmed/30881590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/4248529
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