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Severe Perinatal Hypoxic-Ischemic Brain Injury Induces Long-Term Sensorimotor Deficits, Anxiety-Like Behaviors and Cognitive Impairment in a Sex-, Age- and Task-Selective Manner in C57BL/6 Mice but Can Be Modulated by Neonatal Handling

Perinatal brain injury (PBI) leads to neurological disabilities throughout life, from motor deficits, cognitive limitations to severe cerebral palsy. Yet, perinatal brain damage has limited therapeutic outcomes. Besides, the immature brain of premature children is at increased risk of hypoxic/ischem...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Front Behav Neurosci
Main Authors: Muntsant, Aida, Shrivastava, Kalpana, Recasens, Mireia, Giménez-Llort, Lydia
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6381068/
https://ncbi.nlm.nih.gov/pubmed/30814939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnbeh.2019.00007
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