Severe Perinatal Hypoxic-Ischemic Brain Injury Induces Long-Term Sensorimotor Deficits, Anxiety-Like Behaviors and Cognitive Impairment in a Sex-, Age- and Task-Selective Manner in C57BL/6 Mice but Can Be Modulated by Neonatal Handling

Perinatal brain injury (PBI) leads to neurological disabilities throughout life, from motor deficits, cognitive limitations to severe cerebral palsy. Yet, perinatal brain damage has limited therapeutic outcomes. Besides, the immature brain of premature children is at increased risk of hypoxic/ischem...

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Bibliographische Detailangaben
Veröffentlicht in:Front Behav Neurosci
Hauptverfasser: Muntsant, Aida, Shrivastava, Kalpana, Recasens, Mireia, Giménez-Llort, Lydia
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2019
Schlagworte:
Neuroscience
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6381068/
https://ncbi.nlm.nih.gov/pubmed/30814939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnbeh.2019.00007
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