THE ROLE OF DENDRITIC BRAIN-DERIVED NEUROTROPHIC FACTOR TRANSCRIPTS ON ALTERED INHIBITORY CIRCUITRY IN DEPRESSION

BACKGROUND: A parallel downregulation of brain-derived neurotrophic factor (BDNF) and somatostatin (SST), a marker of inhibitory Y-amino-butyric acid (GABA) interneurons which target pyramidal cell dendrites, has been reported in several brain areas of subjects with major depressive disorder (MDD),...

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Publicado en:Biol Psychiatry
Autores principales: Oh, Hyunjung, Piantadosi, Sean C., Rocco, Brad R., Lewis, David A., Watkins, Simon C., Sibille, Etienne
Formato: Artigo
Lenguaje:Inglês
Publicado: 2018
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6380918/
https://ncbi.nlm.nih.gov/pubmed/30449530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2018.09.026
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