Relationship of Brain-Derived Neurotrophic Factor and Its Receptor TrkB to Altered Inhibitory Prefrontal Circuitry in Schizophrenia

Dysfunction of inhibitory neurons in the prefrontal cortex (PFC), represented by decreased expression of GABA-related genes such as the 67 kDa isoform of glutamate decarboxylase (GAD(67)) and parvalbumin (PV), appears to contribute to cognitive deficits in subjects with schizophrenia. We investigate...

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Detalles Bibliográficos
Publicado en:J Neurosci
Autores principales: Hashimoto, Takanori, Bergen, Sarah E., Nguyen, Quyen L., Xu, Baoji, Monteggia, Lisa M., Pierri, Joseph N., Sun, Zhuoxin, Sampson, Allan R., Lewis, David A.
Formato: Artigo
Lenguaje:Inglês
Publicado: Society for Neuroscience 2005
Materias:
Neurobiology of Disease
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6725470/
https://ncbi.nlm.nih.gov/pubmed/15647480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4035-04.2005
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