The knocking down of the oncoprotein Golgi phosphoprotein 3 in T98G cells of glioblastoma multiforme disrupts cell migration by affecting focal adhesion dynamics in a focal adhesion kinase-dependent manner

Golgi phosphoprotein 3 (GOLPH3) is a conserved protein of the Golgi apparatus that in humans has been implicated in tumorigenesis. However, the precise function of GOLPH3 in malignant transformation is still unknown. Nevertheless, clinicopathological data shows that in more than a dozen kinds of can...

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Bibliografski detalji
Izdano u:PLoS One
Glavni autori: Arriagada, Cecilia, Luchsinger, Charlotte, González, Alexis E., Schwenke, Tomás, Arriagada, Gloria, Folch, Hugo, Ehrenfeld, Pamela, Burgos, Patricia V., Mardones, Gonzalo A.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2019
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6380552/
https://ncbi.nlm.nih.gov/pubmed/30779783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0212321
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