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Functional disruption of the Golgi apparatus protein ARF1 sensitizes MDA-MB-231 breast cancer cells to the antitumor drugs Actinomycin D and Vinblastine through ERK and AKT signaling

Increasing evidence indicates that the Golgi apparatus plays active roles in cancer, but a comprehensive understanding of its functions in the oncogenic transformation has not yet emerged. At the same time, the Golgi is becoming well recognized as a hub that integrates its functions of protein and l...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Luchsinger, Charlotte, Aguilar, Marcelo, Burgos, Patricia V., Ehrenfeld, Pamela, Mardones, Gonzalo A.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5882166/
https://ncbi.nlm.nih.gov/pubmed/29614107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0195401
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