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Promoter capture Hi-C based identification of recurrent non-coding mutations in colorectal cancer

Efforts are being directed to systematically analyse the non-coding genome for cancer-driving mutations1–6. Cis-regulatory elements (CREs) represent a highly enriched subset of the non-coding genome in which to search for such mutations. We use capture Hi-C for 19,023 promoter fragments to catalogue...

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Detalhes bibliográficos
Publicado no:Nat Genet
Main Authors: Orlando, Giulia, Law, Philip J., Cornish, Alex J., Dobbins, Sara E., Chubb, Daniel, Broderick, Peter, Litchfield, Kevin, Hariri, Fadi, Pastinen, Tomi, Osborne, Cameron S., Taipale, Jussi, Houlston, Richard S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6380472/
https://ncbi.nlm.nih.gov/pubmed/30224643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41588-018-0211-z
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