Exploring the fate of inhaled monoclonal antibody in the lung parenchyma by microdialysis

Therapeutic antibodies (Abs) are emerging as major drugs to treat respiratory diseases, and inhalation may provide substantial benefits for their delivery. Understanding the behavior of Abs after pulmonary deposition is critical for their development. We investigated the pharmacokinetics of a nebuli...

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Detalles Bibliográficos
Publicado en:MAbs
Main Authors: Guillon, Antoine, Pardessus, Jeoffrey, Lhommet, Pierre, Parent, Christelle, Respaud, Renaud, Marchand, Denis, Montharu, Jérôme, De Monte, Michèle, Janiak, Philip, Boixel, Christophe, Audat, Héloïse, Huille, Sylvain, Guillot, Etienne, Heuze-Vourc’h, Nathalie
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis 2019
Assuntos:
Short Communication
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6380415/
https://ncbi.nlm.nih.gov/pubmed/30714473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2018.1556081
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