Exploring the fate of inhaled monoclonal antibody in the lung parenchyma by microdialysis

Therapeutic antibodies (Abs) are emerging as major drugs to treat respiratory diseases, and inhalation may provide substantial benefits for their delivery. Understanding the behavior of Abs after pulmonary deposition is critical for their development. We investigated the pharmacokinetics of a nebuli...

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Detalhes bibliográficos
Publicado no:MAbs
Main Authors: Guillon, Antoine, Pardessus, Jeoffrey, Lhommet, Pierre, Parent, Christelle, Respaud, Renaud, Marchand, Denis, Montharu, Jérôme, De Monte, Michèle, Janiak, Philip, Boixel, Christophe, Audat, Héloïse, Huille, Sylvain, Guillot, Etienne, Heuze-Vourc’h, Nathalie
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2019
Assuntos:
Short Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6380415/
https://ncbi.nlm.nih.gov/pubmed/30714473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2018.1556081
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