Paternal genome rescues mouse preimplantation embryo development in the absence of maternally-recruited EZH2 activity

Enhancer of zeste homolog 2 (EZH2), a component of the PRC2 complex, trimethylates H3K27, a transcriptionally repressive histone mark. EZH2 is encoded by a dormant maternal mRNA and inhibiting the maturation-associated increase in EZH2 activity using either a combined siRNA/morpholino approach or a...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Epigenetics
Main Authors: Wang, Huili, Paulson, Erika E, Ma, Libing, Ross, Pablo J, Schultz, Richard M
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2019
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6380398/
https://ncbi.nlm.nih.gov/pubmed/30661456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15592294.2019.1570771
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker