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NEAT1 regulates Th2 cell development by targeting STAT6 for degradation

The aim of this study was to investigate the role of lncRNA NEAT1 (nuclear enriched abundant transcript 1) in regulating Th2 cell differentiation. The overexpression vectors of NEAT1 and ITCH, and siRNA targeting NEAT1, EZH2 (enhancer of zeste homolog 2) and STAT6 (signal transducer and activator of...

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Vydáno v:Cell Cycle
Hlavní autoři: Huang, Shuman, Dong, Dong, Zhang, Yaqian, Chen, Zhuo, Geng, Jing, Zhao, Yulin
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6380394/
https://ncbi.nlm.nih.gov/pubmed/30654703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2018.1562285
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