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Sensing Mitochondrial Acetyl-CoA to Tune Respiration
Fatty acid synthesis (FAS) in mitochondria produces a key metabolite called lipoic acid. However, a new study by Van Vranken et al. [1] (Mol. Cell 2018;71:567–580) shows that mitochondrial FAS regulates the assembly of oxidative phosphorylation complexes, thereby functioning as a nutrient sensor for...
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| Pubblicato in: | Trends Endocrinol Metab |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6380363/ https://ncbi.nlm.nih.gov/pubmed/30442533 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tem.2018.10.003 |
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