Large-scale validation of miRNAs by disease association, evolutionary conservation and pathway activity

The validation of microRNAs (miRNAs) identified by next generation sequencing involves amplification-free and hybridization-based detection of transcripts as criteria for confirming valid miRNAs. Since respective validation is frequently not performed, miRNA repositories likely still contain a subst...

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Vydáno v:RNA Biol
Hlavní autoři: Fehlmann, Tobias, Laufer, Thomas, Backes, Christina, Kahramann, Mustafa, Alles, Julia, Fischer, Ulrike, Minet, Marie, Ludwig, Nicole, Kern, Fabian, Kehl, Tim, Galata, Valentina, Düsterloh, Aneta, Schrörs, Hannah, Kohlhaas, Jochen, Bals, Robert, Huwer, Hanno, Geffers, Lars, Krüger, Rejko, Balling, Rudi, Lenhof, Hans-Peter, Meese, Eckart, Keller, Andreas
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2018
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6380326/
https://ncbi.nlm.nih.gov/pubmed/30567465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2018.1559689
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