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Activation of compensatory pathways via Rac2 in the absence of the Cdc42 effector Wiskott-Aldrich syndrome protein in Dendritic cells

There is extensive crosstalk between different Rho GTPases, including Cdc42, Rac1, and Rac2, and they can activate or inhibit the activity of each other. Dendritic cells express both Rac1 and Rac2. Due to posttranslational modification of lipid anchors, Rac1 localizes mainly to the plasma membrane w...

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Detalhes bibliográficos
Publicado no:Small GTPases
Main Authors: Baptista, Marisa A. P., Westerberg, Lisa S.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6380290/
https://ncbi.nlm.nih.gov/pubmed/28129089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21541248.2016.1275363
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