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Flagellar cAMP signaling controls trypanosome progression through host tissues

The unicellular parasite Trypanosoma brucei is transmitted between mammals by tsetse flies. Following the discovery that flagellar phosphodiesterase PDEB1 is required for trypanosomes to move in response to signals in vitro (social motility), we investigated its role in tsetse flies. Here we show th...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Shaw, Sebastian, DeMarco, Stephanie F., Rehmann, Ruth, Wenzler, Tanja, Florini, Francesca, Roditi, Isabel, Hill, Kent L.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6379439/
https://ncbi.nlm.nih.gov/pubmed/30778051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-08696-y
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