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Flagellar cAMP signaling controls trypanosome progression through host tissues

The unicellular parasite Trypanosoma brucei is transmitted between mammals by tsetse flies. Following the discovery that flagellar phosphodiesterase PDEB1 is required for trypanosomes to move in response to signals in vitro (social motility), we investigated its role in tsetse flies. Here we show th...

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Publicado en:Nat Commun
Autores principales: Shaw, Sebastian, DeMarco, Stephanie F., Rehmann, Ruth, Wenzler, Tanja, Florini, Francesca, Roditi, Isabel, Hill, Kent L.
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6379439/
https://ncbi.nlm.nih.gov/pubmed/30778051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-08696-y
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