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Engineered transfer RNAs for suppression of premature termination codons
Premature termination codons (PTCs) are responsible for 10–15% of all inherited disease. PTC suppression during translation offers a promising approach to treat a variety of genetic disorders, yet small molecules that promote PTC read-through have yielded mixed performance in clinical trials. Here w...
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| Foilsithe in: | Nat Commun |
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| Main Authors: | , , , , , , , , , , |
| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
Nature Publishing Group UK
2019
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6379413/ https://ncbi.nlm.nih.gov/pubmed/30778053 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-08329-4 |
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