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Effects of premature termination codon polymorphisms in the Drosophila pseudoobscura subclade

Premature termination codon (PTC) mutations can have dramatic effects – both adaptive and deleterious – on gene expression and function. Here, we examine the number and selective effects of PTC mutations within the Drosophila pseudoobscura subclade using 18 resequenced genomes aligned to the referen...

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Autors principals: Hoehn, Kenneth B., McGaugh, Suzanne E., Noor, Mohamed A. F.
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3508312/
https://ncbi.nlm.nih.gov/pubmed/23132097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00239-012-9528-x
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