Precise tuning of gene expression levels in mammalian cells

Precise, analogue regulation of gene expression is critical for cellular function in mammals. In contrast, widely employed experimental and therapeutic approaches such as knock-in/out strategies are more suitable for binary control of gene activity. Here we report on a method for precise control of...

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Библиографические подробности
Опубликовано в: :Nat Commun
Главные авторы: Michaels, Yale S., Barnkob, Mike B., Barbosa, Hector, Baeumler, Toni A., Thompson, Mary K., Andre, Violaine, Colin-York, Huw, Fritzsche, Marco, Gileadi, Uzi, Sheppard, Hilary M., Knapp, David J. H. F., Milne, Thomas A., Cerundolo, Vincenzo, Fulga, Tudor A.
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2019
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6379387/
https://ncbi.nlm.nih.gov/pubmed/30778069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-08777-y
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