Astragalin Suppresses Inflammatory Responses and Bone Destruction in Mice With Collagen-Induced Arthritis and in Human Fibroblast-Like Synoviocytes

Astragalin, as a bioactive flavonoid with anti-inflammatory, antioxidant, and protective properties, provides a potential agent for rheumatoid arthritis (RA). In this study, its therapeutic efficacy and the underlying mechanisms were explored using DBA/1J mice with collagen-induced arthritis (CIA)....

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Опубликовано в: :Front Pharmacol
Главные авторы: Jia, Qingyun, Wang, Tengteng, Wang, Xiaoyun, Xu, Hao, Liu, Yang, Wang, Yongjun, Shi, Qi, Liang, Qianqian
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2019
Предметы:
Pharmacology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6379316/
https://ncbi.nlm.nih.gov/pubmed/30809149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.00094
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