Microscopy-Based Automated Live Cell Screening for Small Molecules That Affect Ciliation

The primary monocilium, or cilium, is a single antenna-like organelle that protrudes from the surface of most mammalian cell types, and serves as a signaling hub. Mutations of cilia-associated genes result in severe genetic disorders termed ciliopathies. Among these, the most common is autosomal dom...

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Publicat a:Front Genet
Autors principals: Zhang, Peishan, Kiseleva, Anna A., Korobeynikov, Vladislav, Liu, Hanqing, Einarson, Margret B., Golemis, Erica A.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2019
Matèries:
Genetics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6379280/
https://ncbi.nlm.nih.gov/pubmed/30809247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2019.00075
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