The agonistic TSPO ligand XBD173 attenuates the glial response thereby protecting inner retinal neurons in a murine model of retinal ischemia

BACKGROUND: Ligand-driven modulation of the mitochondrial translocator protein 18 kDa (TSPO) was recently described to dampen the neuroinflammatory response of microglia in a retinal light damage model resulting in protective effects on photoreceptors. We characterized the effects of the TSPO ligand...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Gepubliceerd in:J Neuroinflammation
Hoofdauteurs: Mages, Kristin, Grassmann, Felix, Jägle, Herbert, Rupprecht, Rainer, Weber, Bernhard H. F., Hauck, Stefanie M., Grosche, Antje
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2019
Onderwerpen:
Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6378755/
https://ncbi.nlm.nih.gov/pubmed/30777091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-019-1424-5
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items