Translocator protein (18 kDa) (TSPO) is expressed in reactive retinal microglia and modulates microglial inflammation and phagocytosis

BACKGROUND: The translocator protein (18 kDa) (TSPO) is a mitochondrial protein expressed on reactive glial cells and a biomarker for gliosis in the brain. TSPO ligands have been shown to reduce neuroinflammation in several mouse models of neurodegeneration. Here, we analyzed TSPO expression in mous...

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Main Authors: Karlstetter, Marcus, Nothdurfter, Caroline, Aslanidis, Alexander, Moeller, Katharina, Horn, Felicitas, Scholz, Rebecca, Neumann, Harald, Weber, Bernhard H F, Rupprecht, Rainer, Langmann, Thomas
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2014
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3895821/
https://ncbi.nlm.nih.gov/pubmed/24397957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-11-3
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