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An Isoquinoline Scaffold as a Novel Class of Allosteric HIV-1 Integrase Inhibitors
[Image: see text] Allosteric HIV-1 integrase inhibitors (ALLINIs) are a new class of potential antiretroviral therapies with a unique mechanism of action and drug resistance profile. To further extend this class of inhibitors via a scaffold hopping approach, we have synthesized a series of analogues...
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| Опубликовано в: : | ACS Med Chem Lett |
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| Главные авторы: | , , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Chemical
Society
2019
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| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6378678/ https://ncbi.nlm.nih.gov/pubmed/30783506 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.8b00633 |
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