Frontotemporal dementia is the leading cause of “true” A−/T+ profiles defined with Aβ(42/40) ratio

INTRODUCTION: Patients with positive tauopathy but negative Aβ(42) (A−T+) in the cerebrospinal fluid (CSF) represent a diagnostic challenge. The Aβ(42/40) ratio supersedes Aβ(42) and reintegrates “false” A−T+ patients into the Alzheimer's disease spectrum. However, the biomarker and clinical ch...

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Bibliografiska uppgifter
I publikationen:Alzheimers Dement (Amst)
Huvudupphovsmän: Pouclet-Courtemanche, Hélène, Nguyen, Tri-Bao, Skrobala, Emilie, Boutoleau-Bretonnière, Claire, Pasquier, Florence, Bouaziz-Amar, Elodie, Bigot-Corbel, Edith, Schraen, Susanna, Dumurgier, Julien, Paquet, Claire, Lebouvier, Thibaud
Materialtyp: Artigo
Språk:Inglês
Publicerad: Elsevier 2019
Ämnen:
CSF Biomarkers
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6378630/
https://ncbi.nlm.nih.gov/pubmed/30815533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dadm.2019.01.001
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