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Differential regulation of GSK-3β in spinal dorsal horn and in hippocampus mediated by interleukin-1beta contributes to pain hypersensitivity and memory deficits following peripheral nerve injury
Accumulating evidence shows that inhibition of glycogen synthase kinase-3beta (GSK-3β) ameliorates cognitive impairments caused by a diverse array of diseases. Our previous work showed that spared nerve injury (SNI) that induces neuropathic pain causes short-term memory deficits. Here, we reported t...
Gespeichert in:
Veröffentlicht in: | Mol Pain |
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Hauptverfasser: | , , , , , , , , , , |
Format: | Artigo |
Sprache: | Inglês |
Veröffentlicht: |
SAGE Publications
2019
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Schlagworte: | |
Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6378430/ https://ncbi.nlm.nih.gov/pubmed/30632435 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1744806919826789 |
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