Combining Gene Transfer and Nonhuman Primates to Better Understand and Treat Parkinson’s Disease

Parkinson’s disease (PD) is a progressive CNS disorder that is primarily associated with impaired movement. PD develops over decades and is linked to the gradual loss of dopamine delivery to the striatum, via the loss of dopaminergic (DA) neurons in the substantia nigra pars compacta (SNpc). While t...

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Udgivet i:Front Mol Neurosci
Main Authors: Lasbleiz, Christelle, Mestre-Francés, Nadine, Devau, Gina, Luquin, Maria-Rosario, Tenenbaum, Liliane, Kremer, Eric J., Verdier, Jean-Michel
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2019
Fag:
Neuroscience
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6378268/
https://ncbi.nlm.nih.gov/pubmed/30804750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2019.00010
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