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Dendritic remodeling of D1 neurons by RhoA/Rho-kinase mediates depression-like behavior

Depression alters the structure and function of brain reward circuitry. Preclinical evidence suggests that medium spiny neurons (MSNs) in the nucleus accumbens (NAc) undergo structural plasticity, however the molecular mechanism and behavioral significance is poorly understood. Here we report that a...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Mol Psychiatry
Päätekijät: Fox, Megan E., Chandra, Ramesh, Menken, Miriam S., Larkin, Emily J, Nam, Hyungwoo, Engeln, Michel, Francis, T. Chase, Lobo, Mary Kay
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2018
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6378138/
https://ncbi.nlm.nih.gov/pubmed/30120419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41380-018-0211-5
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