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Acute ethanol exposure promotes autophagy-lysosome pathway-dependent ASIC1a protein degradation and protects against acidosis-induced neurotoxicity

Tissue acidosis is a common feature of brain ischemia which causes neuronal injury. Activation of acid-sensing ion channel 1a (ASIC1a) plays an important role in acidosis-mediated neurotoxicity. Acute ethanol administration has been shown to provide neuroprotective effects during ischemic stroke, bu...

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Bibliografiska uppgifter
I publikationen:Mol Neurobiol
Huvudupphovsmän: Zhou, Ren-Peng, Leng, Tian-Dong, Yang, Tao, Chen, Fei-Hu, Xiong, Zhi-Gang
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2018
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6378129/
https://ncbi.nlm.nih.gov/pubmed/30120732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12035-018-1289-0
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