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Sirt3 suppresses calcium oxalate-induced renal tubular epithelial cell injury via modification of FoxO3a-mediated autophagy

High oxalic acid and calcium oxalate (CaOx)-induced renal tubular epithelial cell (TEC) injury plays a key role in nephrolithiasis. However, the mechanism remains unknown. Gene array analysis of the mice nephrolithiasis model indicated significant downregulation of sirtuin 3 (Sirt3) and activation o...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Cell Death Dis
मुख्य लेखकों: Peng, Yonghan, Yang, Cheng, Shi, Xiaolei, Li, Ling, Dong, Hao, Liu, Changcheng, Fang, Ziyu, Wang, Zeyu, Ming, Shaoxiong, Liu, Min, Xie, Bin, Gao, Xiaofeng, Sun, Yinghao
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Nature Publishing Group UK 2019
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC6377683/
https://ncbi.nlm.nih.gov/pubmed/30674870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-1169-6
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