Barcoding reveals complex clonal behavior in patient-derived xenografts of metastatic triple negative breast cancer

Primary triple negative breast cancers (TNBC) are prone to dissemination but sub-clonal relationships between tumors and resulting metastases are poorly understood. Here we use cellular barcoding of two treatment-naïve TNBC patient-derived xenografts (PDXs) to track the spatio-temporal fate of thous...

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Publié dans:Nat Commun
Auteurs principaux: Merino, D., Weber, T. S., Serrano, A., Vaillant, F., Liu, K., Pal, B., Di Stefano, L., Schreuder, J., Lin, D., Chen, Y., Asselin-Labat, M. L., Schumacher, T. N., Cameron, D., Smyth, G. K., Papenfuss, A. T., Lindeman, G. J., Visvader, J. E., Naik, S. H.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2019
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6377663/
https://ncbi.nlm.nih.gov/pubmed/30770823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-08595-2
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