PLOD3 suppression exerts an anti-tumor effect on human lung cancer cells by modulating the PKC-delta signaling pathway

Current lung cancer treatments are far from satisfactory; thus, finding novel treatment targets is crucial. We recently identified procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 (PLOD3), which is involved in fibrosis and tissue remodeling as a radioresistance-related protein in lung cancer cells...

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Veröffentlicht in:Cell Death Dis
Hauptverfasser: Baek, Jeong-Hwa, Yun, Hong Shik, Kwon, Gyoo Taik, Lee, Janet, Kim, Ju-Young, Jo, Yunhui, Cho, Jae-Min, Lee, Chang-Woo, Song, Jie-Young, Ahn, Jiyeon, Kim, Jae-Sung, Kim, Eun Ho, Hwang, Sang-Gu
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6377650/
https://ncbi.nlm.nih.gov/pubmed/30770789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1405-8
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