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SNARE machinery is optimized for ultrafast fusion

SNARE proteins zipper to form complexes (SNAREpins) that power vesicle fusion with target membranes in a variety of biological processes. A single SNAREpin takes about 1 s to fuse two bilayers, yet a handful can ensure release of neurotransmitters from synaptic vesicles much faster: in a 10th of a m...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Manca, Fabio, Pincet, Frederic, Truskinovsky, Lev, Rothman, James E., Foret, Lionel, Caruel, Matthieu
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6377469/
https://ncbi.nlm.nih.gov/pubmed/30700546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1820394116
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